|
Common Name |
Yohimbine hydrochloride |
||
|
CAS Number |
65-19-0 |
Molecular Weight |
390.904 |
|
Density |
N/A |
Boiling Point |
542.979ºC at 760 mmHg |
|
Molecular Formula |
C21H27ClN2O3 |
Melting Point |
288-290 °C (dec.)(lit.) |
Yohimbine hydrochloride is an α2-adrenergic receptor antagonist and increases the firing rate of the locus coeruleus with a resultant increase in sympathetic outflow (Redmond, 1987). Oral and intravenous yohimbine causes an increase in MHPG and blood pressure in healthy human subjects (Charney et al., 1982d; Goldberg et al., 1986). Depressed patients demonstrate an increased cortisol and blood pressure response to intravenous yohimbine compared with healthy subjects, while plasma MHPG is not significantly different between the two groups of subjects (Heninger et al., 1988). The effects of acute or chronic antidepressant treatments on the neuroendocrine or behavioural responses to yohimbine in depressed patients have not been studied.
Yohimbine hydrochloride has been associated with high blood pressure, increased heart rate, headache, anxiety, dizziness, nausea, vomiting, tremors, and sleeplessness. It can be dangerous if taken in large doses or for long periods of time. It should not be taken in combination with monoamine oxidase (MAO) inhibitors, as effects may be additive.
Yohimbe should be used with caution when taken with medicines for high blood pressure, tricyclic antidepressants, or phenothiazines. People with kidney problems and people with psychiatric conditions should not use yohimbe. Women who are pregnant or breastfeeding should not take yohimbe.
The Journal of Medical Toxicology reports an instance of refractory priapism associated with ingestion of yohimbe extract, and there are other scattered reports of adverse reactions. However, may studies report it to be generally well tolerated.
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Main products
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Product name |
CAS NO. |
Product name |
CAS NO. |
|
PMK powder oil |
28578-16-7 |
2-Bromo-4'-Methylpropiophenone |
1451-82-7 |
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BMK powder |
5449-12-7 |
2-Bromo-1-phenyl-1-pentanone |
49851-31-2 |
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BMK oil |
20320-59-6 |
4'-Methylpropiophenone |
5337-93-9 |
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1, 4-Butanediol |
110-63-4 |
Valerophenone |
1009-14-9 |
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Methylamine hcl |
593-51-1 |
2-Bromo-3-Methylpropiophenone |
1451-83-8 |
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Bromazolam |
71368-80-4 |
2-Iodo-1-P-Tolylpropan-1-One |
236117-38-7 |
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Flubrotizolam |
57801-95-3 |
Xylazine |
7361-61-7 |
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Tadalafil |
171596-29-5 |
Levamisole |
14769-73-4 |
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Sildenafil |
139755-83-2 |
Benzocaine |
94-09-7 |
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Pregabalin |
148553-50-8 |
Tetracaine hcl |
136-47-0 |
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Isopropylbenzylamine |
102-97-6 |
Lidocaine hcl |
73-78-9 |
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Phenacetin |
62-44-2 |
Procaine hcl |
51-05-8 |
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Boric acid |
11113-50-1 |
Tetracaine |
94-24-6 |
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Paracetamol |
103-90-2 |
procaine |
59-46-1 |
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Pyrrolidine |
123-75-1 |
Dimethocaine |
94-15-5 |
Packing&Shipping
1. Package: 25kg / 170kg / 230kg drum
2. Shipment: Shipping by Fedex, DHL, EMS or TNT; Shipping by Air or by Sea
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1) Most items are in large stock, so the products can be sent out within 24 hours after payment confirmed, tracking number and packing details will be informed as soon as possible;
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